Join our team to study the role of Trop2 expression in metastasis.
What we offer:
A 4-year Ph.D. position in cancer research is available under the Animal Physiology, Immunology, and Developmental Biology program at the Faculty of Science, MUNI in Brno, Czech Republic. The studentship is funded and includes a part-time grant position. Excellent administrative and technical support is provided.
Who we are looking for:
We are looking forward to it!
Please submit your application (CV & motivation letter) before March 29th, 2024.
The team’s primary research interest is to understand the plasticity and heterogeneity of cancer cells and the role of the tumor microenvironment in the regulation of cancer progression. Cellular plasticity has been considered as a factor contributing to resistance to cancer chemotherapy and poor prognosis. At the same time, recurrence and chemoresistance of many types of cancers are believed to be strongly connected with the biology of cancer stem-like cells or tumor-initiating cells (CSCs/TICs) and circulating tumor cells (CTCs). There is increasing evidence that cancer plasticity induced by different stimuli is a source of CSCs/TICs/CTCs. The group analyzes phenotypic characteristics of single cells or single cell-derived clones and cell-cell interactions to understand better molecular mechanisms associated with cell plasticity and its role in cancer progression and generation of the cells with CSCs/TICs/CTCs-like properties.